The decline of Venice didn’t end with the loss of statehood. Attempts at modernising Venice have failed, and the result is an economic monoculture of mass tourism, and a constant demographic decline.
Venice produced and exported Theriac, an ancient wonder medicine for just about every ailment imaginable. It was a flourishing business for centuries, and an important part of the Venetian economy.
During the 1400s, Venice had created defences against the recurring outbreaks of the plague, and they kept Venice mostly safe for the following centuries. Mostly safe.
The story of Bianca Cappello tells us something about the institutions of the Republic of Venice, the agility of its government, and of early modern diplomacy.