Venice became a more important state in the 1000s and 1100s, and started to build not only their trading empire, but also more equal relations to the Byzantine Empire, the Holy Roman Empire and the Pope in Rome.
Venice produced and exported Theriac, an ancient wonder medicine for just about every ailment imaginable. It was a flourishing business for centuries, and an important part of the Venetian economy.
During the 1400s, Venice had created defences against the recurring outbreaks of the plague, and they kept Venice mostly safe for the following centuries. Mostly safe.
The story of Bianca Cappello tells us something about the institutions of the Republic of Venice, the agility of its government, and of early modern diplomacy.
