The 1400s and 1500s were centuries of enormous change for Venice, and for the rest of the world. The changing geography moved Venice from a central position in European trade to the margins.
Venice produced and exported Theriac, an ancient wonder medicine for just about every ailment imaginable. It was a flourishing business for centuries, and an important part of the Venetian economy.
During the 1400s, Venice had created defences against the recurring outbreaks of the plague, and they kept Venice mostly safe for the following centuries. Mostly safe.
The story of Bianca Cappello tells us something about the institutions of the Republic of Venice, the agility of its government, and of early modern diplomacy.
